解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:The Computer Adaptive Test version of the Community Reintegration of Injured Service Members measure (CRIS-CAT) consists of three scales measuring Extent of, Perceived Limitations in, and Satisfaction with community integration. The CRIS-CAT was developed using item response theory methods. The purposes of t...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-145
更新日期:2012-09-17 00:00:00
abstract:BACKGROUND:We developed and validated an automated database case definition for diabetes in children and youth to facilitate pharmacoepidemiologic investigations of medications and the risk of diabetes. METHODS:The present study was part of an in-progress retrospective cohort study of antipsychotics and diabetes in Te...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-128
更新日期:2012-08-24 00:00:00
abstract:BACKGROUND:The development of risk prediction models is of increasing importance in medical research - their use in practice, however, is rare. Among other reasons this might be due to the fact that thorough validation is often lacking. This study focuses on two Bayesian approaches of how to validate a prediction rule ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-99
更新日期:2012-07-20 00:00:00
abstract:BACKGROUND:Retaining participants in cohort studies with multiple follow-up waves is difficult. Commonly, researchers are faced with the problem of missing data, which may introduce biased results as well as a loss of statistical power and precision. The STROBE guidelines von Elm et al. (Lancet, 370:1453-1457, 2007); V...
journal_title:BMC medical research methodology
pub_type: 杂志文章,评审
doi:10.1186/1471-2288-12-96
更新日期:2012-07-11 00:00:00
abstract:BACKGROUND:Statistical time series derived from administrative data sets form key indicators in measuring progress in addressing disadvantage in Aboriginal and Torres Strait Islander populations in Australia. However, inconsistencies in the reporting of Indigenous status can cause difficulties in producing reliable ind...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-90
更新日期:2012-07-02 00:00:00
abstract:BACKGROUND:Aboriginal and Torres Strait Islander peoples are under-reported in administrative health datasets in NSW, Australia. Correct reporting of Aboriginal and Torres Strait Islander peoples is essential to measure the effectiveness of policies and programmes aimed at reducing the health disadvantage experienced b...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-91
更新日期:2012-07-02 00:00:00
abstract:BACKGROUND:Researchers and policy makers have determined that accounting for productivity costs, or "indirect costs," may be as important as including direct medical expenditures when evaluating the societal value of health interventions. These costs are also important when estimating the global burden of disease. The ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-87
更新日期:2012-06-25 00:00:00
abstract:BACKGROUND:Multistate models have become increasingly useful to study the evolution of a patient's state over time in intensive care units ICU (e.g. admission, infections, alive discharge or death in ICU). In addition, in critically-ill patients, data come from different ICUs, and because observations are clustered int...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-79
更新日期:2012-06-15 00:00:00
abstract:BACKGROUND:Multiple Imputation as usually implemented assumes that data are Missing At Random (MAR), meaning that the underlying missing data mechanism, given the observed data, is independent of the unobserved data. To explore the sensitivity of the inferences to departures from the MAR assumption, we applied the meth...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-73
更新日期:2012-06-08 00:00:00
abstract:BACKGROUND:Compliance is a critical issue for parental questionnaires in school based epidemiological surveys and high compliance is difficult to achieve. The objective of this study was to determine trends and factors associated with parental questionnaire compliance during respiratory health surveys of school childre...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-53
更新日期:2012-04-20 00:00:00
abstract:BACKGROUND:Physical activity is an important determinant of health. Walking is the most common physical activity performed by adults and the presence of sidewalks along roads is a determinant of walking. Geographic information systems (GIS) can be used to measure sidewalks; however, GIS sidewalk data are difficult to a...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-39
更新日期:2012-03-29 00:00:00
abstract:BACKGROUND:The weighted estimators generally used for analyzing case-cohort studies are not fully efficient and naive estimates of the predictive ability of a model from case-cohort data depend on the subcohort size. However, case-cohort studies represent a special type of incomplete data, and methods for analyzing inc...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-24
更新日期:2012-03-09 00:00:00
abstract:BACKGROUND:Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death in Australia, and there are marked differences in mortality trends between men and women. In this study, we have sought to model and forecast age related changes in COPD mortality over time for men and women separately...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-17
更新日期:2012-02-21 00:00:00
abstract:BACKGROUND:The construction of prediction intervals (PIs) for future body mass index (BMI) values of individual children based on a recent German birth cohort study with n = 2007 children is problematic for standard parametric approaches, as the BMI distribution in childhood is typically skewed depending on age. METHO...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-6
更新日期:2012-01-25 00:00:00
abstract:BACKGROUND:In Routine Outcome Monitoring (ROM) there is a high demand for short assessments. Computerized Adaptive Testing (CAT) is a promising method for efficient assessment. In this article, the efficiency of a CAT version of the Mood and Anxiety Symptom Questionnaire, - Anhedonic Depression scale (MASQ-AD) for use ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-12-4
更新日期:2012-01-10 00:00:00
abstract:BACKGROUND:Technical advances following the Human Genome Project revealed that high-quality and -quantity DNA may be obtained from whole saliva samples. However, usability of previously collected samples and the effects of environmental conditions on the samples during collection have not been assessed in detail. In fi...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-170
更新日期:2011-12-19 00:00:00
abstract::The recently published "COSMIN" guidelines aim to rate properties of outcome instruments and state two issues with regard to responsiveness which is the instrument's ability to detect change over time. These issues are comparison of score changes with change of an external criterion using correlations and the judgemen...
journal_title:BMC medical research methodology
pub_type: 评论,信件
doi:10.1186/1471-2288-11-152
更新日期:2011-11-18 00:00:00
abstract:BACKGROUND:There is a recognised need to build primary care medication adherence services which are tailored to patients' needs. Continuous quality improvement of such services requires a regular working method of measuring adherence in order to monitor effectiveness. Self report has been considered the method of choic...
journal_title:BMC medical research methodology
pub_type: 杂志文章,评审
doi:10.1186/1471-2288-11-149
更新日期:2011-11-03 00:00:00
abstract:BACKGROUND:The Public Population Project in Genomics (P3G) is an organisation that aims to promote collaboration between researchers in the field of population-based genomics. The main objectives of P3G are to encourage collaboration between researchers and biobankers, optimize study design, promote the harmonization o...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-135
更新日期:2011-10-05 00:00:00
abstract:BACKGROUND:Evidence suggests that differences exist in physical activity (PA) participation among Culturally and Linguistically Diverse (CALD) children and adolescents. It is possible that these differences could be influenced by variations in measurement technique and instrument reliability. However, culturally sensit...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-122
更新日期:2011-08-25 00:00:00
abstract:BACKGROUND:In the present article, we propose an alternative method for dealing with negative affectivity (NA) biases in research, while investigating the association between a deleterious psychosocial environment at work and poor mental health. First, we investigated how strong NA must be to cause an observed correlat...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-121
更新日期:2011-08-24 00:00:00
abstract:BACKGROUND:Nowadays, more and more clinical scales consisting in responses given by the patients to some items (Patient Reported Outcomes - PRO), are validated with models based on Item Response Theory, and more specifically, with a Rasch model. In the validation sample, presence of missing data is frequent. The aim of...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-105
更新日期:2011-07-14 00:00:00
abstract:BACKGROUND:The term 'inequities' refers to avoidable differences rooted in injustice. This review examined whether or not, and how, quantitative studies identifying inequalities in risk factors and health service utilization for asthma explicitly addressed underlying inequities. Asthma was chosen because recent decades...
journal_title:BMC medical research methodology
pub_type: 杂志文章,评审
doi:10.1186/1471-2288-11-104
更新日期:2011-07-12 00:00:00
abstract:BACKGROUND:Cluster randomised controlled trials (CRCTs) are frequently used in health service evaluation. Assuming an average cluster size, required sample sizes are readily computed for both binary and continuous outcomes, by estimating a design effect or inflation factor. However, where the number of clusters are fix...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-102
更新日期:2011-06-30 00:00:00
abstract:BACKGROUND:The Community Reintegration of Service Members (CRIS) is a new measure of community reintegration developed to measure veteran's participation in life roles. It consists of three sub-scales: Extent of Participation (Extent), Perceived Limitations with Participation (Perceived), and Satisfaction with Particip...
journal_title:BMC medical research methodology
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2288-11-98
更新日期:2011-06-25 00:00:00
abstract:BACKGROUND:How overall physical activity relates to specific activities and how reported activity changes over time may influence interpretation of observed associations between physical activity and health. We examine the relationships between various physical activities self-reported at different times in a large coh...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-97
更新日期:2011-06-22 00:00:00
abstract:BACKGROUND:Evidence mapping describes the quantity, design and characteristics of research in broad topic areas, in contrast to systematic reviews, which usually address narrowly-focused research questions. The breadth of evidence mapping helps to identify evidence gaps, and may guide future research efforts. The Globa...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-92
更新日期:2011-06-17 00:00:00
abstract:BACKGROUND:Both scientists and the public routinely refer to randomized controlled trials (RCTs) as being the 'gold standard' of scientific evidence. Although there is no question that placebo-controlled RCTs play a significant role in the evaluation of new pharmaceutical treatments, especially when it is important to ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-65
更新日期:2011-05-11 00:00:00
abstract:BACKGROUND:For practical reasons it is not easy to obtain fasting samples in large population health surveys. Non-fasting triglyceride (Tg) values are difficult to interpret. The authors compared the accuracy of statistically corrected non-fasting Tg values with true fasting values and estimated the misclassification o...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-63
更新日期:2011-05-10 00:00:00
abstract:BACKGROUND:The prevailing view in therapeutic clinical research today is that observational studies are useful for generating new hypotheses and that controlled experiments (i.e., randomized clinical trials, RCTs) are the most appropriate method for assessing and confirming the efficacy of interventions. DISCUSSION:Th...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-57
更新日期:2011-04-25 00:00:00
abstract:BACKGROUND:Glaucoma is a leading cause of avoidable blindness worldwide. Open angle glaucoma is the most common type of glaucoma. No randomised controlled trials have been conducted evaluating the effectiveness of glaucoma screening for reducing sight loss. It is unclear what the most appropriate intervention to be eva...
journal_title:BMC medical research methodology
pub_type: 临床试验,杂志文章
doi:10.1186/1471-2288-11-54
更新日期:2011-04-21 00:00:00
abstract:BACKGROUND:Estimating costs is essential to the economic analysis of health care programs. Health care costs are often captured from administrative databases or by patient report. Administrative records only provide a partial representation of health care costs and have additional limitations. Patient-completed questio...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-45
更新日期:2011-04-13 00:00:00
abstract:BACKGROUND:The primary aim of this study was to provide an estimate of effect size for the functional outcome of operative versus non-operative treatment for patients with an acute rupture of the Achilles tendon using accelerated rehabilitation for both groups of patients. The secondary aim was to assess the use of a c...
journal_title:BMC medical research methodology
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2288-11-39
更新日期:2011-04-05 00:00:00
abstract:BACKGROUND:Meta-analysis typically involves combining the estimates from independent studies in order to estimate a parameter of interest across a population of studies. However, outliers often occur even under the random effects model. The presence of such outliers could substantially alter the conclusions in a meta-a...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-19
更新日期:2011-02-16 00:00:00
abstract:BACKGROUND:Route environments can positively influence people's active commuting and thereby contribute to public health. The Active Commuting Route Environment Scale (ACRES) was developed to study active commuters' perceptions of their route environments. However, bicycle commuters represent a small portion of the pop...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-6
更新日期:2011-01-17 00:00:00
abstract:BACKGROUND:Data on lifetime exposures are often self-reported in epidemiologic studies, sometimes many years after the relevant age. Validity of self-reported data is usually inferred from their agreement with measured values, but few studies directly quantify the likely effects of reporting errors in body size and rep...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-11-7
更新日期:2011-01-17 00:00:00
abstract:BACKGROUND:In prognostic studies model instability and missing data can be troubling factors. Proposed methods for handling these situations are bootstrapping (B) and Multiple imputation (MI). The authors examined the influence of these methods on model composition. METHODS:Models were constructed using a cohort of 58...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-10-81
更新日期:2010-09-17 00:00:00
abstract:BACKGROUND:A zero-inflated continuous outcome is characterized by occurrence of "excess" zeros that more than a single distribution can explain, with the positive observations forming a skewed distribution. Mixture models are employed for regression analysis of zero-inflated data. Moreover, for repeated measures zero-i...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-10-55
更新日期:2010-06-14 00:00:00
abstract:BACKGROUND:The collection of individual-level pandemic (H1N1) 2009 influenza immunization data was considered important to facilitate optimal vaccine delivery and accurate assessment of vaccine coverage. These data are also critical for research aimed at evaluating the new vaccine's safety and effectiveness. Systems us...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-10-51
更新日期:2010-06-08 00:00:00
abstract:BACKGROUND:The systematic collection of high-quality mortality data is a prerequisite in designing relevant drowning prevention programmes. This descriptive study aimed to assess the quality (i.e., level of specificity) of cause-of-death reporting using ICD-10 drowning codes across 69 countries. METHODS:World Health O...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/1471-2288-10-30
更新日期:2010-04-08 00:00:00